Comparative of Chemical Methods for Determination Cephalexinmonohydrate- A Review

Cephalexin is broadly utilized against both Gram positive also Gram negative microbes. The physiochemical properties sway the choice of proper detailing forms (1)It is important to estimate and detect amount of antibiotics in pharmaceutical and clinical samples because of their numerous pathological procedures. This is vital in a field of human wellbeing and aging industry for checking illicit utilization of anti-infection agents in food saving also handling (2).Chromatographic methods using various detectors, due to simultaneous detection, accurate quantification, automation and the high selectivity based on the chemical structures of the analyte, have been the most commonly used for the detection of antibiotics (3-5). Cephalosporins were established by titrimetric (6-8), Spectrophotometry (9-11), fluorimetry (18,19), chemiluminescence (20), chromatography(22-26), potentiometer(27), alsovoltammetry (28,29) methods.

Keywords: Cephalexin monohydrate,a review, HPlC, Atomic spectroscopy, flame ionization spectrophotomtry, electrochemical, thermal Analysis.